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Estudos sobre covid19
Aqui estao os estudos cientificos que servem de base para as respostas do programa "Como-curar-coronavirus"








REFERÊNCIAS

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30.Gautret, P., Lagier, J.C., Parola, P., Meddeb, L., Mailhe, M., Doudier, B., Courjon, J., Giordanengo, V., Vieira, V.E., Dupont, H.T. and Honoré, S., 2020. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents, p.105949.

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46.Liu, J., Cao, R., Xu, M., Wang, X., Zhang,H., Hu, H., Li, Y., Hu, Z., Zhong, W. and Wang, M., 2020. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discovery, 6(1), pp.1-4.

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64.Shibata M, Aoki H, Tsurumi T, et al. Mechanism of uncoating of influenza B virus in MDCK cells: action of chloroquine. J Gen Virol 1983; 64: 1149–56.

65.Silva APR, Vitolo MR, Zara LF et al. Effects of zinc supplementation on 1-to 5-year old children. Jornal de Pediatria-Vol. 82, Nº3, 2006, 227-231.

66.Singh AK, Singh A, Shaikh A, Singh R, Misra A, Chloroquine and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: A systematic search and a narrative review with a special reference to India and other developing countries, Diabetes & Metabolic Syndrome: Clinical Research & Reviews (2020), doi: https://doi.org/10.1016/j.dsx.2020.03.011.

67.Smith ER, Klein-Schwartz W. Are 1–2 dangerous? Chloroquine and hydroxychloroquine exposure in toddlers. The Journal of Emergency Medicine, 2005; 28: 437-443).

68.Tang et al. Hydroxychloroquine in patients mainly with mild to moderate COVID–19: an open–label, randomized, controlled trial. medRxiv preprint doi: https://doi.org/10.1101/2020.04.10.20060558.

69.Van Thuan Hoang, Valérie Giordanengo,Vera Esteves Vieira, Hervé Tissot Dupont, Philippe Colson , Eric Chabriere, Bernard La Scola, Jean-Marc Rolain,Didier Raoult , Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of anopen-label non-randomized clinical trial, International Journal of Antimicrobial Agents (2020), doi: https://doi.org/10.1016/j.ijantimicag.2020.105949.

70.Vincent MJ, Bergeron E, Benjannet S, et al. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virol J 2005; 2: 69.

71.Vincent, M.J., Bergeron, E., Benjannet, S., Erickson, B.R., Rollin, P.E., Ksiazek, T.G., Seidah, N.G. and Nichol, S.T., 2005. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virology journal, 2(1), p.69.

72.Wang, M. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 30, 269–271 (2020).

73.Yao et al., 2020. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

74.Yao, X., Ye, F., Zhang, M., Cui, C., Huang, B., Niu, P., Liu, X., Zhao, L., Dong, E., Song, C. and Zhan, S., 2020. In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical Infectious Disease.

75.Yu et al. Hydroxychloroquine application is associated with a decreased mortality in critically ill patients with COVID-19. medRxiv preprint doi: https://doi.org/10.1101/2020.04.27.20073379.

76.Zhaoet al. Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening. Eur J Clin Microbiol Infect Dis. 2020 Apr 23 : 1–12. doi:10.1007/s10096-020-03897-6

77.Estes estudos foram aplicados com sucesso pelas prefeituras de "Porto Feliz - sp", "Itajai - sc", algumas da Bahia e alumas do Rio rande do Sul. Existe na internet muitas reportagens sobre estes casos.

78. https://portalnovonorte.com.br/?p=35011
reproduz um artigo do conceituado "The American Journal od Medicine" onde se defende o tratamento preventivo contra Covid19 e informa que o rasil é lider mundial em numero de recuperados.



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